RESULTS

The most basic and easily readable result – the dose response at different time windows and for both single and continuous/repetitive exposure (i.e. as a replacement for various OECD TGs)

The unique In finite result – the time evolution of inflammation for various doses and for both single and continuous/repetitive exposure, by which we significantly upgrade the information delivered by the OECD TGs

The most powerful long-term assessment at once – the dose-time contour plot with predicted inflammation status over range of doses and times that allows the customer to:

  • Select the time window and type of exposure and read out the LOAEL doses accordingly to best reflect the investigated conditions,
  • identify the inflammation resolution time for any dose,
  • identify how dose effect adds up nonlinearly with time, significantly exceeding the information delivered by the OECD TGs

Evolution of the dose driven by biology with estimated dynamics for the ratio between available and unavailable dose (aggregated, quarantined, dissolved)

The raw microscopy data, that is acquired for every material exposure during in vitro monitoring to allow our customers to search for the phenomena that might be visible in the images but are not explicitly taken into account during translation and prediction of inflammation

Povečava GIF-a